Multiparametric MR-PET measurements in hypermetabolic regions reflect differences in molecular status and tumor grade in treatment-naïve diffuse gliomas.

Hiroyuki Tatekawa Akifumi Hagiwara Hiroyuki Uetani Jingwen Yao Talia C Oughourlian Shadfar Bahri Chencai Wang Catalina Raymond Albert Lai Timothy F Cloughesy Phioanh Leia Nghiemphu Linda M Liau Whitney B Pope Noriko Salamon Benjamin M Ellingson

Published in: Journal of neuro-oncology (2020)

FDOPA hypermetabolic ROI may extract useful imaging features of gliomas, which can illuminate biological differences between different molecular status or tumor grades.

Keyphrases

high grade
high resolution
computed tomography
oxidative stress
single molecule
magnetic resonance imaging
mass spectrometry
positron emission tomography
pet imaging
combination therapy