Whole genome resequencing of the Iranian native dogs and wolves to unravel variome during dog domestication.

Zeinab Amiri GhanatsamanGuo-Dong WangHojjat Asadollahpour NanaeiMasood Asadi FoziMin-Sheng PengAli EsmailizadehYa-Ping Zhang

Published in: BMC genomics (2020)

Our results showed more deleterious mutations and coding sequence variants in the domestic dog genome than those in wolf genome. By providing the first Iranian dog and wolf variome map, our findings contribute to understanding the genetic architecture of the dog domestication.

Keyphrases

genome wide
copy number
dna methylation
gene expression
high density