Three days of high-dose glucocorticoid treatment attenuates large-vessel 18F-FDG uptake in large-vessel giant cell arteritis but with a limited impact on diagnostic accuracy.

Berit Dalsgaard NielsenLars Christian GormsenIb Tønder HansenKresten Krarup KellerPhilip TherkildsenEllen-Margrethe Hauge

Published in: European journal of nuclear medicine and molecular imaging (2018)

Within 3 days of high-dose glucocorticoid treatment, FDG PET/CT can diagnose LV-GCA with high sensitivity. This window of opportunity ensures that prompt glucocorticoid treatment can be initiated to avoid debilitating GCA complications with a limited effect on diagnostic accuracy. After 10 days of treatment, FDG PET/CT sensitivity decreases significantly.

Keyphrases

high dose
low dose
risk factors
giant cell