Three days of high-dose glucocorticoid treatment attenuates large-vessel 18F-FDG uptake in large-vessel giant cell arteritis but with a limited impact on diagnostic accuracy.
Berit Dalsgaard NielsenLars Christian GormsenIb Tønder HansenKresten Krarup KellerPhilip TherkildsenEllen-Margrethe HaugePublished in: European journal of nuclear medicine and molecular imaging (2018)
Within 3 days of high-dose glucocorticoid treatment, FDG PET/CT can diagnose LV-GCA with high sensitivity. This window of opportunity ensures that prompt glucocorticoid treatment can be initiated to avoid debilitating GCA complications with a limited effect on diagnostic accuracy. After 10 days of treatment, FDG PET/CT sensitivity decreases significantly.
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