Salvage therapies for biochemical recurrence after definitive local treatment: a systematic review, meta-analysis, and network meta-analysis.
Akihiro MatsukawaShahrokh F ShariatTamas FazekasMarcin MiszczykIchiro TsuboiMehdi Kardoust PariziEkaterina LaukhtinaJakob KlemmStefano ManconKeiichiro MoriShoji KimuraJun MikiGómez Rivas JuanTimo F W SoeterikThomas ZilliDerya TilkiSteven JoniauTakahiro KimuraShahrokh F ShariatPaweł RajwaPublished in: Prostate cancer and prostatic diseases (2024)
The combination of prostate bed RT, elective pelvic irradiation, and ADT is the preferred treatment for eligible patients with post-RP BCR based on our analysis. In remaining patients, or in case of post-RT recurrence, especially for those with high-risk BCR, the combination of ADT and ARSI should be considered.