The evolution of a series of behavioral traits is associated with autism-risk genes in cavefish.

Masato YoshizawaAlexander SettleMeredith C HermosuraLillian J TuttleNicolas CetraroCourtney N PassowSuzanne E McGaugh

Published in: BMC evolutionary biology (2018)

Overall, our study indicates that ASD-risk genes and associated pathways (especially digestive, immune and metabolic pathways) may be repeatedly used for shifts in polygenic behaviors across evolutionary time.

Keyphrases

genome wide
autism spectrum disorder
intellectual disability
dna methylation
attention deficit hyperactivity disorder
genome wide identification
gene expression
genome wide analysis