Brain metastases in patients with upper gastrointestinal cancer is associated with proximally located adenocarcinoma and lymph node metastases.
Kazuto HaradaHyunsoo HwangXuemei WangAhmed AbdelhakeemMasaaki IwatsukiMariela A Blum MurphyDipen M MaruBrian WestonJeffrey H LeeJane E RogersAllison TrailNamita ShanbhagMeina ZhaoManoop S BhutaniQuynh-Nhu NguyenStephen G SwisherNaruhiko IkomaPrajnan DasWayne L HofstetterBrian D BadgwellJaffer A AjaniPublished in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2020)
Patients with proximally located adenocarcinoma, or with lymph node metastases are at a higher risk for BRMs and patients fare better after treatment of isolated BRM.