En face slab optical coherence tomography imaging successfully monitors progressive degenerative changes in the innermost layer of the diabetic retina.

Atsuko KatsuyamaSentaro KusuharaShun-Ichiro AsaharaShun-Ichiro NakaiSotaro MoriWataru MatsumiyaAkiko MikiTakuji KurimotoHisanori ImaiYoshiaki KidoWataru OgawaMakoto Nakamura

Published in: BMJ open diabetes research & care (2021)

En face slab OCT imaging would be a novel useful modality for the assessment of diabetic retinal neurodegeneration as it could detect subtle optical changes occurring in the innermost retina in diabetic eyes. Our animal experimental data suggest that dark areas observed on en face slab OCT images might be the impairment of the extracellular matrix as well as neurons.

Keyphrases

optical coherence tomography
diabetic retinopathy
optic nerve
extracellular matrix
high resolution
type diabetes
wound healing
multiple sclerosis
spinal cord
spinal cord injury
mass spectrometry
high speed
deep learning
electronic health record
convolutional neural network
artificial intelligence
data analysis