Impact of the Innate Inflammatory Response on ICU Admission and Death in Hospitalized Patients with COVID-19.
Jorge Monserrat SanzAngel Asúnsolo-Del BarcoAna Maria GómezMiguel Ángel OrtegaJose Maria GasallaÓscar GasullaJordi Fortuny-ProfitósFerran A Mazaira-FontMiguel Teixidó RománAlberto ArranzJosé SanzBenjamin MuñozJuan Arévalo-SerranoJosé Miguel RodríguezCarlos Martínez-ADimitri BalomenosMelchor Álvarez-MonPublished in: Biomedicines (2021)
When severe COVID-19 progresses to ICU admission and/or death there is a marked increase in serum levels of several cytokines and chemokines, mainly related to the patient's inflammatory IR. Serum levels of IL-10, IL-6 and GCSF were most prognostic of the outcome measure.