Diagnosing Alzheimer's disease specifically and sensitively with pLG72 and cystine/glutamate antiporter SLC7A11 as blood biomarkers.

The findings suggest that pLG72 protein and SLC7A11 mRNA can distinguish AD patients from healthy controls with excellent specificity and sensitivity, respectively. The combination of pLG72 and SLC7A11 yields better AUC than either, suggesting the superiority of simultaneously measuring both biomarkers in identifying AD patients.