Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage.
Hideki NakamotoYuki KatanosakaRyota ChijimatsuDaisuke MoriFengjun XuanFumiko YanoYasunori OmataYuji MaenoharaYasutaka MurahashiKohei KawaguchiRyota YamagamiHiroshi InuiShuji TaketomiYuki TaniguchiMotoi KanagawaKeiji NaruseSakae TanakaTaku SaitoPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
Our findings demonstrate regulation of articular cartilage by TRPV2 through Prg4 induction and suppression of ectopic ossification.