Chronic Hepatitis E is associated with cholangitis.
Andrea BeerHeidemarie HolzmannSven PischkePatrick BehrendtFritz WrbaJerome SchlueUta DrebberBarbara NeudertEmina HalilbasicHans KreipeAnsgar Wilhelm LohseMartina SterneckHeiner WedemeyerMichael MannsHans P DienesPublished in: Liver international : official journal of the International Association for the Study of the Liver (2019)
Chronic hepatitis E in immunocompromised individuals runs a similar course as hepatitis B and C and shows similar histopathology. However, the presence of destructive cholangitis in some cases accompanied by an increased number of polymorphonuclear leucocytes is markedly different. Immunohistochemically the virus is present in bile duct epithelia, seemingly the cause for cholangitis.