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The impact of cut-off values on the prevalence of short cervical length in pregnancy.

Sofie H BreukingCharlotte E van DijkAnnabelle L van GilsMaud D van ZijlBrenda M KazemierE Pajkrtnull null
Published in: European journal of obstetrics, gynecology, and reproductive biology (2024)
This study demonstrates that using any cut-off value for a short CL influences the incidence and distribution of CL. When using a cut-off value of ≤35 mm for study inclusion, the incidence of measurements of a short CL is lower than the anticipated incidence compared to a normal distribution. However, when using a cut-off value of ≤25 mm for progesterone treatment, the frequency of CL measurements is higher than expected below this threshold compared to a normal distribution. This study highlights the risk of introducing selection bias, most likely unintentionally, when cut-off values for short CL are used, regardless of the specific value chosen. Therefore healthcare providers should measure the CL with caution if essential decisions depend on a specific cut-off value.
Keyphrases
  • healthcare
  • risk factors
  • combination therapy
  • replacement therapy