Rare NOTCH3 Variants in a Chinese Population-Based Cohort and Its Relationship With Cerebral Small Vessel Disease.

Jing-Yi LiuMing YaoYi DaiFei HanFei-Fei ZhaiDing-Ding ZhangLi-Xin ZhouJun NiShu-Yang ZhangLi-Ying CuiYi-Cheng Zhu

Published in: Stroke (2021)

Carriers of rare NOTCH3 variants involving the EGFr domain may be genetically predisposed to age-related cerebral small vessel disease in the general Chinese population.

Keyphrases

subarachnoid hemorrhage
copy number
small cell lung cancer
cell proliferation
epidermal growth factor receptor
tyrosine kinase
gene expression