Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression.

LeeAnn RamsayMarie-Lise QuilléCyrille OrsetPierre de la GrangeEstelle RousseletClaude FérecGérald Le GacEmmanuelle GéninSerge Timsit

Published in: Annals of clinical and translational neurology (2019)

Common gene expression profile can be identified in the brain and blood and clearly differentiates ischemic from nonischemic conditions. Therefore, specific blood transcriptomic signature may represent a surrogate for brain ischemic gene expression.

Keyphrases

gene expression
cerebral ischemia
dna methylation
resting state
white matter
single cell
subarachnoid hemorrhage
blood brain barrier
rna seq
brain injury