Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis.
María I ZuluagaSusana Otero-RomeroAlex RoviraSantiago Perez-HoyosGeorgina ArrambideLaura NegrottoIngrid GalánJordi RíoManuel ComabellaCarlos NosMaría Jesús ArévaloAngela Vidal-JordanaJoaquin CastillóBreogán RodríguezLuciana MidagliaPatricia MuleroRaquel MitjanaCristina AugerJaume Sastre-GarrigaXavier MontalbanMar TintorePublished in: Neurology (2019)
These results demonstrate that menarche, pregnancies, and breastfeeding did not substantially modify the risk of CDMS or disability accrual using a multivariable and time-dependent approach.