Polymorphisms of dopamine pathway genes NRG1 and LMX1A are associated with cognitive performance in bipolar disorder.

Sindre RolstadErik PålssonCarl Johan EkmanElias ErikssonCarl SellgrenMikael Landén

Published in: Bipolar disorders (2015)

The risk variants of the rs35753505 SNP were associated with increased performance in several cognitive domains and IQ, whereas the risk variants of the rs11809911 SNP in LMX1A was associated with reduced IQ and memory/learning.

Keyphrases

bipolar disorder
genome wide
copy number
major depressive disorder
dna methylation
working memory
high density
gene expression
transcription factor
genome wide identification