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Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae.

Jenny M GreenwoodBarbara MilutinovićRobert PeußSarah BehrensDaniela EsserPhilip RosenstielHinrich SchulenburgJoachim Kurtz
Published in: BMC genomics (2017)
Our data demonstrate that gene expression upon infection is strongly affected by previous immune priming. We hypothesise that this shift in gene expression indicates activation of a more targeted and efficient response towards a previously encountered pathogen, in anticipation of potential secondary encounter.
Keyphrases
  • gene expression
  • dna methylation
  • electronic health record
  • machine learning
  • big data
  • candida albicans
  • risk assessment