Functional domains of SP110 that modulate its transcriptional regulatory function and cellular translocation.

Jia-Shiun LeuSo-Yi ChangChia-Yu MuMei-Ling ChenBo-Shiun Yan

Published in: Journal of biomedical science (2018)

The findings from this study elucidating the multidomain structure of the SP110 not only identify functional domains of SP110 that are required for transcriptional regulation, cellular translocation, and protein interactions but also implicate that SP110 has additional functions through its unexpected activity in the nucleolus.

Keyphrases

transcription factor
gene expression
binding protein
protein protein