Ultrasound erosions in the feet best predict progression to inflammatory arthritis in anti-CCP positive at-risk individuals without clinical synovitis.
Andrea Di MatteoKulveer MankiaLaurence DuquenneEdoardo CipollettaRichard J WakefieldLeticia Garcia-MontoyaJacqueline Leong NamPaul EmeryPublished in: Annals of the rheumatic diseases (2020)
In CCP+ at-risk individuals, BE in the feet appear to precede the onset of clinical synovitis. BE in >1 joint, and BE in combination with US synovitis in the MTP5 joints, are the most predictive for the development of clinical arthritis.