Taste receptor type 1 member 3 enables western diet-induced anxiety in mice.

Jae Won SongKeon-Hee LeeHobin SeongDong-Mi ShinWoo-Jeong Shon

Published in: BMC biology (2023)

Our results imply that TAS1R3 may play a key role in WD-induced alterations in hypothalamic functions, and that inhibition of TAS1R3 overactivation in the hypothalamus could offer therapeutic targets to alleviate the effects of WD on anxiety.

Keyphrases

sleep quality
high glucose
diabetic rats
high fat diet induced
drug induced
oxidative stress
endothelial cells
depressive symptoms
metabolic syndrome
stress induced