Genetic determinants of SARS-CoV-2 and the clinical outcome of COVID-19 in Southern Bangladesh.

Md. Mahbub Hasan Chayan Kumar SahaH M Hamidullah MehediKallyan ChakmaAsma SalauddinMd Shakhawat HossainFarjana SharmenS M Rafiqul IslamAfroza Akter TanniFarhana YasminAl-Shahriar AkashMohammad Enayet HossainMojnu MiahSanjoy Kanti BiswasNahid SultanaAdnan Mannan

Published in: Immunity, inflammation and disease (2024)

Our study identifies some risk factors such as age comorbidities (diabetes, hypertension, and renal disease) that are associated with severe COVID-19, providing valuable insight regarding prioritizing vaccination for high-risk individuals and allocating health care and resources. The findings of this work outlined the knowledge and mutational basis of SARS-CoV-2 for the next treatment steps. Further studies are needed to confirm the effects of structural and functional proteins of SARS-CoV-2 in detail for monitoring the emergence of new variants in future.

Keyphrases

sars cov
healthcare
risk factors
respiratory syndrome coronavirus
genome wide
blood pressure
type diabetes
copy number
cardiovascular disease
gene expression
dna methylation
metabolic syndrome
adipose tissue
skeletal muscle
replacement therapy
combination therapy
insulin resistance
social media
smoking cessation