The immune response to sub-clinical mastitis is impaired in HIV-infected women.
Roxane SchaubStéphanie BadiouJohannes ViljoenPierre DujolsKarine BolloréPhilippe Van de PerreMarie-Louise NewellRuth BlandNicolas NagotEdouard TuaillonPublished in: Journal of translational medicine (2018)
HIV infection in ART-naïve women was associated with elevated breast milk levels of IP-10 and MIG, which areTh1-related cytokines induced by IFN-γ. During SCM, a lower and narrower immune response was observed in HIV-infected than HIV-uninfected women, suggesting that HIV infection affects the capacity of the mammary gland to respond to SCM.