Human skin biomarkers relationship to response to treatment with tyrosine kinase inhibitors in advanced EGFR-mutated lung adenocarcinoma.
Anahí Castañeda-ZárragaJerónimo Rafael Rodríguez-CidRodrigo Rafael Flores-MariñelarenaHéctor Trinidad-BibianoJosé Fabián Martínez-HerreraCarla Paola Sánchez-RíosValeria Michelle Fernández-GaribayJorge Arturo Alatorre-AlexanderLuis Martínez-BarreraPatricio Javier Santillán-DohertyMaría Elisa Vega-MemijePublished in: Thoracic cancer (2020)
The relationship between EGFR pathway inhibition in the skin and oncological outcomes obtained explains the parallel biological effects of tyrosine kinase inhibitors. We hope that our work incites future research to help validate and assess the use of these markers as potential prognostic and predictive factors.