Extracellular Vesicles, Inflammation, and Cardiovascular Disease.
Akbarshakh AkhmerovTanyalak ParimonPublished in: Cells (2022)
Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms of most cardiovascular disorders involve innate and adaptive immune responses, and extracellular vesicles are implicated in both. In this review, we describe the mechanistic role of extracellular vesicles at the intersection of inflammatory processes and cardiovascular disease. Our discussion focuses on atherosclerosis, myocardial ischemia and ischemic heart disease, heart failure, aortic aneurysms, and valvular pathology.
Keyphrases
- cardiovascular disease
- immune response
- heart failure
- left ventricular
- oxidative stress
- type diabetes
- atrial fibrillation
- aortic valve
- cardiovascular risk factors
- cardiovascular events
- toll like receptor
- cardiac resynchronization therapy
- pulmonary artery
- coronary artery
- pulmonary arterial hypertension
- pulmonary hypertension
- metabolic syndrome