β6-Integrin Serves as a Potential Serum Marker for Diagnosis and Prognosis of Pancreatic Adenocarcinoma.
Daniela LenggenhagerSusan BengsRalph FritschSaskia HussungPhilipp BusenhartKatharina EndhardtAntonia TöpferFrans Olivier TheSimon BütikoferChristoph GublerMichael ScharlBernhard MorellPublished in: Clinical and translational gastroenterology (2021)
Our findings suggest that ITGB6 might serve as a novel serum biomarker for early diagnosis and prognosis of PAC. Given the limited specificity and sensitivity of currently used carbohydrate antigen 19-9-based assays, ITGB6 may have the potential to improve the diagnostic accuracy for PAC.