Cervical and systemic innate immunity predictors of HIV risk linked to genital herpes acquisition and time from HSV-2 seroconversion.

Yashini GovenderCharles S MorrisonPai-Lien ChenXiaoming GaoHidemi YamamotoTsungai ChipatoSharon AndersonRobert BarbieriRobert SalataGustavo F DoncelRaina Nakova Fichorova

Published in: Sexually transmitted infections (2022)

A combination of systemic immunoinflammatory and cervical immunosuppressed states predicts HSV-2 acquisition. A persistently suppressed innate immunity during incident HSV-2 infection may add to the increased HIV-1 susceptibility.

Keyphrases

herpes simplex virus
antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
cardiovascular disease
type diabetes