IL-17 Promotes Nitric Oxide Production in Non-Small-Cell Lung Cancer.
Stefania NicolaIrene RidolfiGiovanni RollaPierluigi FilossoRoberto GiobbeMonica BoitaBeatrice CullaCaterina BuccaPaolo SolidoroLuisa BrussinoPublished in: Journal of clinical medicine (2021)
This is the first report assessing a relationship between FeNO levels and Th17-related cytokines in the EBC of patients affected by early-stage NSCLC. IL-17, which could promote angiogenesis through the VEGF pathway, might be indirectly responsible for the increased lung production of NO in patients with NSCLC.
Keyphrases
- early stage
- nitric oxide
- small cell lung cancer
- end stage renal disease
- endothelial cells
- ejection fraction
- vascular endothelial growth factor
- newly diagnosed
- chronic kidney disease
- advanced non small cell lung cancer
- peritoneal dialysis
- prognostic factors
- radiation therapy
- squamous cell carcinoma
- hydrogen peroxide
- patient reported outcomes
- tyrosine kinase