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Accuracy and comparison of two rapid multiplex PCR tests for gastroenteritis pathogens: a systematic review and meta-analysis.

Li-Jun ChangChun-Jen HsiaoBing ChenTzu-Yu LiuJulia DingWan-Ting HsuVictor Su-OrtizSzu-Ta ChenKe-Ying SuHan-Ping WuChien-Chang Lee
Published in: BMJ open gastroenterology (2021)
This is the first meta-analysis that is a head-to-head comparison examining the performance of the novel multiplex PCR-based tests Luminex xTAG GPP and FilmArray GI panel in detecting each pathogen. Point estimates calculated from eligible studies showed that both GI panels are highly accurate and may provide important diagnostic information for early identification of gastroenteritis. In addition, although FilmArray has higher sensitivity and post-test probability than xTAG GPP for most of the pathogens, how this will translate to a clinical setting remains unclear.
Keyphrases
  • real time pcr
  • systematic review
  • case control
  • high throughput
  • gram negative
  • optic nerve
  • antimicrobial resistance
  • meta analyses
  • healthcare
  • social media
  • loop mediated isothermal amplification