Association of soluble TREM-like transcript-1 with clinical features and patient reported outcomes in systemic lupus erythematosus.

Ileana Vázquez-Otero Yerania Rodríguez-Navedo Karina Vilá-Rivera Mariely Nieves-Plaza Jessica Morales-Ortiz A Valance Washington Luis M Vilá

Published in: European journal of rheumatology (2018)

Compared with healthy individuals, sTLT-1 levels were significantly lower in patients with SLE. Among patients with SLE, correlations were observed for some domains of LupusPRO. Given that sTLT-1 has anti-inflammatory properties, the deficiency of this protein could play an important role in the pathogenesis of SLE.

Keyphrases

systemic lupus erythematosus
patient reported outcomes
disease activity
anti inflammatory
rheumatoid arthritis
protein protein
amino acid
binding protein
small molecule