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A Cohort Study to Evaluate Genetic Predictors for Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS): Results from ECOG-ACRIN E1Z11.

Vered StearnsOpeyemi A JagedeVictor Tsu-Shih ChangTodd C SkaarJeffrey L BerenbergRanveer NandAtif ShafqatNisha Lassi JacobsWilliam LuginbuhlPaul GilmanAl Bowen BensonJudie R GoodmanGary L BuchschacherNorah L HenryCharles L LoprinziPatrick J FlynnEdith P MitchellMichael Jordan FischJoseph A SparanoLynne I Wagner
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
We were unable to prospectively validate candidate SNPs previously associated with AI discontinuation due to AIMSS. Future analyses will explore additional genetic markers, PRO predictors of AIMSS, and differences by race.
Keyphrases
  • genome wide
  • copy number
  • dna methylation
  • artificial intelligence
  • current status
  • gene expression
  • anti inflammatory
  • sleep quality