Steroid affected cytokines in aspirin-exacerbated respiratory disease.
Li Hui TanCailu LinHeather UngererAnkur KumarAnas QatananiNithin D AdappaJames N PalmerJohn V BossoDanielle ReedNoam A CohenMichael A KohanskiPublished in: International forum of allergy & rhinology (2022)
In the epithelial samples, type 2-associated cytokines IL-5 and IL-33, the anti-inflammatory cytokine IL-10, and IFN-γ were lower in AERD patients treated with prednisone. This work serves as a basis to assess therapeutic-induced mucosal cytokine responses in AERD and indicates that the site of cytokine measurement is an important consideration when assessing results.