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Intestinal Epithelial Deletion of Sphk1 Prevents Colitis-Associated Cancer Development by Inhibition of Epithelial STAT3 Activation.

Seung Bin ParkByung-Il ChoiBeom Jae LeeNam Joo KimYoon A JeongMoon Kyung JooHyo Jung KimJong-Jae ParkJae Seon KimYoon-Seok NohHyun Joo Lee
Published in: Digestive diseases and sciences (2019)
Epithelial conditional deletion of Sphk1 inhibits CAC in ApcMin/+-DSS models in mice by inhibiting STAT3 activation and its target signaling pathways.
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