Bufalin stimulates antitumor immune response by driving tumor-infiltrating macrophage toward M1 phenotype in hepatocellular carcinoma.
Zhuo YuYuyao LiYue LiJinghao ZhangMan LiLongshan JiYifei TangYanxi ZhengJianguo ShengQiucheng HanFu LiJianfeng GuoLingtai WangXuehua SunYueqiu GaoHai FengPublished in: Journal for immunotherapy of cancer (2022)
These data expound a novel antitumor mechanism of bufalin, and facilitate exploitation of a new potential macrophage-based HCC immunotherapeutic modality.