Aberrant Salience? Brain Hyperactivation in Response to Pain Onset and Offset in Fibromyalgia.
Catherine S HubbardAsimina LazaridouChristine M CahalanJieun KimRobert R EdwardsVitaly NapadowMarco L LoggiaPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
Our results suggest that the increased sensitivity exhibited by FM patients in response to the onset and offset of painful stimuli may reflect a more generalized hypersensitivity to salient sensory events, and that brain hyperactivation may be a mechanism potentially involved in the generalized hypervigilance to salient stimuli in FM.