Effects of Malate Ringer's solution on myocardial injury in sepsis and enforcement effects of TPP@PAMAM-MR.

Lei TanHan SheJie ZhengXiaoyong PengNingke GuoBindan ZhangYue SunChunhua MaShenglian XuDaiqin BaoYuanqun ZhouQinghui LiQingxiang MaoLiangming LiuYi HuTao Li

Published in: Journal of translational medicine (2022)

MR was suitable for protecting myocardial injury after sepsis. The mechanism was related to MR improving the function and morphology of cardiomyocyte mitochondria and inhibiting cardiomyocyte apoptosis. The protective effect of TPP-MR was superior to MR.

Keyphrases

contrast enhanced
magnetic resonance
acute kidney injury
intensive care unit
cell death
oxidative stress
magnetic resonance imaging
septic shock
computed tomography
endoplasmic reticulum stress
reactive oxygen species
endothelial cells
cell proliferation
drug induced