Predictors of Long-Term Survival in Pancreatic Ductal Adenocarcinoma after Pancreatectomy: TP53 and SMAD4 Mutation Scoring in Combination with CA19-9.

Masato OnoYusuke OnoToru NakamuraTakahiro TsuchikawaTomotaka KurayaShota KuwabaraYoshitsugu NakanishiToshimichi AsanoAya MatsuiKimitaka TanakaYuma EbiharaYo KurashimaTakehiro NojiSoichi MurakamiToshiaki ShichinoheTomoko MitsuhashiYuko OmoriToru FurukawaKenzui TaniueMayumi SuzukiAyumu SugitaniHidenori KarasakiYusuke MizukamiSatoshi Hirano

Published in: Annals of surgical oncology (2022)

Genetic information, i.e., TP53 mutation types and SMAD4 abnormalities, combined with CA19-9, will be a valuable tool for improving surgical strategies for pancreatic cancer.

Keyphrases

epithelial mesenchymal transition
transforming growth factor
protein kinase
genome wide
health information
gene expression
signaling pathway