Assessment and comparative study of diosgenin doses in alleviating experimental periodontitis.

Alper Kızıldağ Aysan Lektemür Alpan Tuğba Köseoğlu Aydın Melih Ozdede Ozlem Ozmen

Published in: BMC oral health (2024)

Collectively, our findings suggest that DG administration protects rats from periodontal tissue damage with a dose-dependent manner, provides an increase in markers of bone formation, decreases in Bax/Bcl-2 ratio and osteoclast activation.

Keyphrases

oxidative stress
induced apoptosis
bone loss