mRNA expression analysis confirms CD44 splicing impairment in systemic lupus erythematosus patients.

Andrea LatiniLucia NovelliFulvia CeccarelliCristiana BarbatiCarlo PerriconeGiada De BenedittisFabrizio ContiGiuseppe NovelliCinzia CiccacciPaola Borgiani

Published in: Lupus (2021)

In SLE patients, the increase in CD44v6 protein correlates with a higher transcript level of this isoform, confirming an impairment of CD44 splicing in the disease, whose regulatory mechanisms require further investigation.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
systemic lupus erythematosus
transcription factor
small molecule
disease activity
single cell