Multiple Meningiomas as a Criterion for the Diagnosis of Neurofibromatosis Type 2 and Other Tumor Predisposition Syndromes.
Cathal John HannanCharlotte Hammerbeck-WardOmar Nathan PathmanabanMiriam J SmithScott A RutherfordSimon K LloydSimon Richard Mackenzie FreemanAndrew J WallaceAndrew Thomas KingDafydd Gareth Richard EvansPublished in: Neurosurgery (2022)
Patients presenting with UVS and MM are significantly more likely to have a nonrefuted diagnosis of NF2 than patients presenting with UVS and ≥2 NIDS, but significantly less likely to develop bilateral VS. Seven percent of those presenting with MM without meeting NF2 criteria had PV in SMARCE1, and 5% had mosaic NF2.