Optimization, in vitro release and toxicity evaluation of novel pH sensitive itaconic acid-g-poly(acrylamide)/sterculia gum semi-interpenetrating networks.

Fauzia RehmanIkram Ullah KhanSyed Haroon KhalidSajid AsgharMuhammad IrfanIkrima KhalidAkhtar RasulHuma MahmoodAbid Mehmood YousafYasser ShahzadMuhammad MudassarNoor Ul Amin Mohsin

Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2021)

Conclusively, developed biocompatible semi-IPN hydrogels with sufficient pH sensitivity and mechanical strength could serve as a potential carrier for intestinal delivery of CTZ HCL to maximize its absorption and reduce side effects.

Keyphrases

drug release
drug delivery
oxidative stress
hyaluronic acid
human health
wound healing
climate change
oxide nanoparticles