Untargeted GC/TOFMS unravel metabolic profiles in cerebrospinal fluid of Chinese people living with HIV.

Alim Keram Ning Pei Tangkai Qi Jingna Xun Yutong Gu Wenwei Li

Published in: Journal of clinical laboratory analysis (2021)

Metabolic profiles were significantly altered in CSF and might play key roles in the etiology of cognitive impairment of PHLIV. Further explore the exact mechanism for these metabolic changes might be useful for cognitive impairment management of PHLIV.

Keyphrases

cognitive impairment
cerebrospinal fluid
density functional theory
high resolution
simultaneous determination
tandem mass spectrometry