Hypo-glycosylated hFSH drives ovarian follicular development more efficiently than fully-glycosylated hFSH: enhanced transcription and PI3K and MAPK signaling.

Guohua HuaJitu W GeorgeKendra L ClarkKim C JonasGillian P JohnsonSiddesh SouthekalChittibabu GudaXiaoying HouHaley R BlumJames EudyViktor Y ButnevAlan R BrownSahithi KattaJeffrey V MayGeorge R Bousfield John S Davis

Published in: Human reproduction (Oxford, England) (2021)

This work was supported by NIH 1P01 AG029531, NIH 1R01 HD 092263, VA I01 BX004272, and the Olson Center for Women's Health. JSD is the recipient of a VA Senior Research Career Scientist Award (1IK6 BX005797). This work was also partially supported by National Natural Science Foundation of China (No. 31872352). The authors declared there are no conflicts of interest.

Keyphrases

public health
healthcare
polycystic ovary syndrome
signaling pathway
mental health
quality improvement
oxidative stress
transcription factor
quantum dots
health information
medical students
pi k akt
cervical cancer screening
insulin resistance
health promotion
metabolic syndrome
pregnant women
skeletal muscle