Correlation of Lung Damage on CT Scan with Laboratory Inflammatory Markers in COVID-19 Patients: A Single-Center Study from Romania.
Cosmin CîtuOana-Maria GorunAndrei Gheorghe Marius MotocIoana Mihaela CituFlorin GorunDaniel MalitaPublished in: Journal of clinical medicine (2022)
(1) Background: This study aims to evaluate the association of CRP, NLR, IL-6, and Procalcitonin with lung damage observed on CT scans; (2) Methods: A cross-sectional study was performed among 106 COVID-19 patients hospitalized in Timisoara Municipal Emergency Hospital. Chest CT and laboratory analysis were performed in all patients. The rank Spearmen correlation was used to assess the association between inflammatory markers and lung involvement. In addition, ROC curve analysis was used to determine the accuracy of inflammatory markers in the diagnosis of severe lung damage; (3) Results: CRP, NLR, and IL-6 were significantly positively correlated with lung damage. All inflammatory markers had good accuracy for diagnosis of severe lung involvement. Moreover, IL-6 has the highest AUC- ROC curve; (4) Conclusions: The inflammatory markers are associated with lung damage and can be used to evaluate COVID-19 severity.
Keyphrases
- computed tomography
- oxidative stress
- sars cov
- dual energy
- contrast enhanced
- end stage renal disease
- healthcare
- coronavirus disease
- image quality
- emergency department
- chronic kidney disease
- newly diagnosed
- positron emission tomography
- magnetic resonance imaging
- ejection fraction
- prognostic factors
- pet ct
- respiratory syndrome coronavirus
- data analysis