Delayed alveolar bone repair and osteonecrosis associated with Zoledronic Acid therapy in rats: macroscopic, microscopic and molecular analysis.
Gustavo Zanna FerreiraEdson Virgílio Zen FilhoIzabel Regina Fischer Rubira-BullenGustavo Pompermaier GarletCarlos Ferreira Dos SantosPaulo Sérgio da Silva SantosPublished in: Journal of applied oral science : revista FOB (2020)
The results highlighted strong and evident interference of zoledronic acid in bone repair of the socket, causing osteonecrosis and delayed bone remodeling.