ISSLS Prize in Bioengineering Science 2023: Age- and sex-related differences in lumbar intervertebral disc degeneration between patients with chronic low back pain and asymptomatic controls.

Noah B BonnheimAnn A LazarAnika KumarZehra AkkayaJiamin ZhouXiaojie GuoConor O'NeillThomas M LinkJeffrey C LotzRoland KrugAaron J Fields

Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2023)

Aging effects on the biochemical composition of the L5-S1 disc may involve a relatively uniform set of factors from which many cLBP patients deviate. NP-T1ρ values at L5-S1 may be highly relevant to clinical phenotyping, particularly in younger individuals.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
public health
minimally invasive
patient reported outcomes
patient reported
single cell