An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report.
Zemni InesHaddad SabrineFatma SaadallahAyadi Mohamed AliCharfi LamiaChargui RiadhRahal KhaledPublished in: Journal of investigative medicine high impact case reports (2021)
Merkel cell carcinoma (MCC) is a rare malignant neuroendocrine tumor more common in immunosuppressed old patients. It is characterized by a high frequency of local recurrence, regional nodal metastasis, distant metastasis, and low survival rate. The diagnosis of MCC is challenging due to its rarity and can be clinically mistaken for other skin cancer. We report a case of locally advanced MCC of the left groin with aggressive behavior that was finally controlled with a combined treatment and we collected data from the literature to discuss the appropriate therapeutic algorithm for the management of this uncommon skin tumor.
Keyphrases
- high frequency
- skin cancer
- transcranial magnetic stimulation
- locally advanced
- end stage renal disease
- neoadjuvant chemotherapy
- lymph node
- ejection fraction
- squamous cell carcinoma
- chronic kidney disease
- free survival
- deep learning
- prognostic factors
- clinical trial
- electronic health record
- soft tissue
- big data
- wound healing
- combination therapy
- data analysis
- phase ii study
- open label
- case report
- replacement therapy
- placebo controlled