Diabetes Mellitus Is a Strong Independent Negative Prognostic Factor in Patients with Brain Metastases Treated with Radiotherapy.

Seong JeongSoniya PoudyalSabine KlaggesThomas KuhntKirsten PapsdorfPeter HambschJohannes WachErdem GüresirFranziska NäglerAlexander RühleNils H NicolayClemens Seidel

Published in: Cancers (2023)

DM is associated with reduced survival in patients with BM. Further research is necessary to better understand the molecular mechanisms and therapeutic implications of this important interaction.

Keyphrases

brain metastases
prognostic factors
small cell lung cancer
glycemic control
early stage
locally advanced
radiation therapy
radiation induced
free survival
type diabetes
squamous cell carcinoma
rectal cancer
adipose tissue
insulin resistance
weight loss