FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal-type.

Costantino Ricci Francesca Ambrosi Tania Franceschini Francesca GiunchiGiorgia Di FilippoEugenia FranchiniFrancesco Massari Veronica Mollica Valentina Tateo Federico Mineo Bianchi Maurizio Colecchia Andres Martin Acosta Michelangelo Fiorentino

Published in: Histopathology (2023)

FoxA2 is a highly sensitive and specific biomarker that supports the diagnosis of YSTpt. FoxA2 is superior to GPC3 and AFP, especially in rare and difficult-to-diagnose histological patterns of YSTpt, but mature glands of Tpt could represent a potential diagnostic pitfall.

Keyphrases

mass spectrometry
fluorescent probe
risk assessment
high resolution