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Universal digital high-resolution melting for the detection of pulmonary mold infections.

Tyler GoshiaApril AralarNathan P WiederholdJeffrey D JenksSanjay R MehtaAprajita KarmakarMonish E SAnkit SharmaHaoxiang SunRefilwe KebadirengPhilip Lewis WhiteMridu SinhaMartin HoeniglStephanie I Fraley
Published in: Journal of clinical microbiology (2024)
Improvements in diagnostics for invasive mold infections are urgently needed. This work presents a new molecular detection approach that addresses technical and workflow challenges to provide fast pathogen detection, identification, and quantification that could inform treatment to improve patient outcomes.
Keyphrases
  • high resolution
  • loop mediated isothermal amplification
  • real time pcr
  • label free
  • pulmonary hypertension
  • mass spectrometry
  • electronic health record
  • candida albicans
  • tandem mass spectrometry