Exposures to 2,4-Dichlorophenoxyacetic acid with or without endotoxin upregulate small cell lung cancer pathway.

Geetika KaurB V Sunil KumarBaljit SinghRam Saran Sethi

Published in: Journal of occupational medicine and toxicology (London, England) (2021)

Taken together, the data show exposures to high and low dose of 2,4-D with/without LPS induced lung inflammation and altered pulmonary transcriptome profile with the involvement of the SCLC pathway. The data from the study provide the insights of the potential damage on lungs caused by 2,4-D and help to better understand the mechanism of this complex relation.

Keyphrases

lps induced
small cell lung cancer
low dose
inflammatory response
oxidative stress
electronic health record
air pollution
big data
pulmonary hypertension
gene expression
high dose
rna seq
single cell
machine learning
brain metastases
dna methylation